Directeur de Recherche
Plateau technique – TofSims
alain brunelle at cnrs fr
Alain Brunelle est directeur de Recherche (DR1) au CNRS. Ancien élève de l’École Normale Supérieure de Saint-Cloud, il a obtenu en 1990 son doctorat en physique et spectrométrie de masse à l’Université Paris-Sud, Orsay, sous la direction d’Yvon Le Beyec. Durant cette période et jusqu’en 2002, à l’Institut de Physique Nucléaire d’Orsay, il étudiait les interactions de particules énergétiques (ions, agrégats, molécules, photons) avec la matière. Il étudia particulièrement l’émission ionique secondaire et la pulvérisation sous l’impact d’agrégats ayant des énergies allant de quelques keV à plusieurs dizaines de MeV, menant en parallèle des développements instrumentaux, analyseurs par temps de vol, nouvelles sources de désorption-ionisation, systèmes de détection. De 2002 à 2018 à l’Institut de Chimie des Substances Naturelles (ICSN, Gif-sur-Yvette), il a ensuite développé un projet d’imagerie biologique par spectrométrie de masse cluster-TOF-SIMS et MALDI-TOF. De 2010 à 2018, Alain Brunelle a été le responsable de l’équipe de spectrométrie de masse de l’ICSN. Depuis 2019, Alain Brunelle commence un nouveau projet au Laboratoire d’Archéologie Moléculaire et Structurale (LAMS UMR8220, CNRS, Université de la Sorbonne, Paris) visant à étudier des échantillons du patrimoine culturel, en particulier les tableaux anciens, à l’aide de l’imagerie par spectrométrie de masse TOF-SIMS, avec une résolution inférieure au micron et des analyses en profondeur (3-D).
- Researcher ID www.researcherid.com/rid/L-3889-2013
- Orcid http://orcid.org/0000-0001-6526-6481
- Scopus https://www.scopus.com/authid/detail.uri?authorId=7004373267
- Google Scholar https://scholar.google.com/citations?user=ReGjGmMAAAAJ&hl=en
Vidéos de Conférences grand public:
- Au Collège de France (2014) https://www.college-de-france.fr/site/philippe-walter/seminar-2014-05-05-11h30.htm
- À l’Université de Strasbourg (2018) https://pod.unistra.fr/video/20740-de-la-biologie-au-patrimoine-avec-limagerie-moleculaire-par-spectrometrie-de-masse
- Conférence future : SIMS 24, 24th International Conference on Secondary Ion Mass Spectrometry, 10-15 Sept. 2023, La Rochelle, France, https://www.sims-24.com/default.aspx
Contact
Disciplines
- Chimie/Chimie analytique64
- Chimie/Chimie organique56
- Physique [physics]/Physique Nucléaire Expérimentale [nucl-ex]25
- Physique [physics]/Physique [physics]/Instrumentations et Détecteurs [physics.ins-det]21
- Chimie16
- Sciences du Vivant [q-bio]/Biologie cellulaire12
- Physique [physics]/Physique [physics]/Agrégats Moléculaires et Atomiques [physics.atm-clus]9
- Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC]/Neurobiologie5
- Planète et Univers [physics]/Sciences de la Terre4
- Informatique [cs]/Traitement du signal et de l'image [eess.SP]3
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biochimie [q-bio.BM]3
- Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC]3
- Sciences du Vivant [q-bio]3
- Chimie/Chemo-informatique2
- Physique [physics]/Physique [physics]/Physique Atomique [physics.atom-ph]2
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire2
- Sciences du Vivant [q-bio]/Ingénierie biomédicale/Imagerie2
- Sciences de l'Homme et Société/Archéologie et Préhistoire2
- Sciences de l'Homme et Société/Art et histoire de l'art2
- Sciences de l'Homme et Société/Héritage culturel et muséologie2
- Chimie/Matériaux1
- Informatique [cs]/Imagerie médicale1
- Physique [physics]/Astrophysique [astro-ph]/Cosmologie et astrophysique extra-galactique [astro-ph.CO]1
- Physique [physics]/Physique [physics]/Physique Générale [physics.gen-ph]1
- Planète et Univers [physics]/Océan, Atmosphère1
- Planète et Univers [physics]/Sciences de la Terre/Géochimie1
- Planète et Univers [physics]/Sciences de la Terre/Paléontologie1
- Sciences du Vivant [q-bio]/Alimentation et Nutrition1
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biophysique1
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biologie structurale [q-bio.BM]1
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Génomique, Transcriptomique et Protéomique [q-bio.GN]1
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Réseaux moléculaires [q-bio.MN]1
- Sciences du Vivant [q-bio]/Bio-Informatique, Biologie Systémique [q-bio.QM]1
- Sciences du Vivant [q-bio]/Biologie végétale/Botanique1
- Sciences du Vivant [q-bio]/Ecologie, Environnement/Interactions entre organismes1
- Sciences du Vivant [q-bio]/Médecine humaine et pathologie1
- Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Bactériologie1
- Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Mycologie1
- Sciences du Vivant [q-bio]/Microbiologie et Parasitologie1
- Sciences de l'Homme et Société/Etudes de l'environnement1
- Sciences de l'ingénieur [physics]1
Mots-clefs
Auteurs
- Brunelle Alain126
- Brunelle A.96
- Touboul David58
- Le Beyec Y.49
- Della-Negra S.37
- Laprévote Olivier37
- Depauw J.27
- Jacquet D.21
- Della Negra S.19
- Laprévote O.19
- Pautrat M.18
- Bouvier Caroline17
- Touboul D.15
- Walter Philippe15
- Seyer Alexandre9
- Hakansson P.8
- Bich Claudia8
- de Viguerie Laurence8
- Andersen H.H.7
- Joret H.7
- Römpp Andreas7
- Touboul David7
- Elie Nicolas7
- Schmitz-Afonso Isabelle7
- Chabot M.6
- Chaurand P.6
- Della-Negra Serge6
- Fallavier M.6
- Wien K.6
- van Nuffel Sebastiaan6
- Richardin Pascale6
- van Nuffel Sebastiaan6
- Fu Tingting6
- Baudin K.5
- Benabdellah Farida5
- Bouneau S.5
- Gardes D.5
- Glanville Helen5
- Nectoux M.5
- Wohrer K.5
- Desbenoit Nicolas5
- Vernhet Dominique5
- Laprévote Olivier5
- Champy Pierre4
- Debois D.4
- Debois Delphine4
- Duyckaerts Charles4
- Kadar Hanane4
- Le Caër Jean-Pierre4
- Schoppmann C.4
- Voit H.4
- Dauphin Y.4
- Vanbellingen Quentin4
- de La Porte Sabine4
- Farre B.4
- Benguerba M.3
- Bernier P.3
- Bertrand-Michel Justine3
- Both Jean-Pierre3
- Boussofiane-Baudin K.3
- Flamant G.3
- Gaudin Mathieu3
- Guettier C.3
- Haakansson P.3
- Laplaze D.3
- Le Naour F.3
- Le Naour François3
- Lebrun M.3
- Mazel Vincent3
- Merucci Chiara3
- Méjean Marie3
- Niehuis Ewald3
- Noun Manale3
- Novikov A.3
- Panchal Maï3
- Parilis E.3
- Petit Vanessa W3
- Poizat J.-C.3
- Richardin P.3
- Rosé Gauthier3
- Spengler Bernhard3
- Stoeckli Markus3
- Sundqvist B.U.R.3
- Thomas J.-P.3
- Tomaschko C.3
- Walter Philippe3
- Pouyet Emeline3
- Cournut Aline3
- Vanbellingen Quentin P.3
- Giuliani Alexandre3
- Walter P.3
- Cuif J.P.3
- Eparvier Véronique3
- Guérineau Vincent3
- Cersoy Sophie3
- Dumas P.3
- Amusant Nadine3
- Abbas Imane2
- Amar Majid2
- Baptista G.B.2
- Baranov I.2
- Barlo Daya D.D.N.2
- Bonneau N.2
- Bonneau Natacha2
- Bouvier C.2
- Briedis Vitalis2
- Cantiello Michela2
- Canut B.2
- Cerruti Christopher D2
- Champy P.2
- Chaurand Pierre2
- Collet Xavier2
- Dauphinot Luce2
- Demaye Anais2
- Deprun C.2
- Desbenoit Nicolas2
- Fisher Gregory L.2
- Fritsch Janine2
- Gardès D.2
- Hallen A.2
- Hamze Kassem2
- Herrera-Durigneux Tomas2
- Hester Alfons2
- Holland I Barry2
- Kirillov S.2
- Klinkert Ivo2
- Kollmer Felix2
- Laboureur Laurent2
- Laprevote O.2
- Le Ven Jessica2
- Lewin Guy2
- Lopes Philippe2
- Marquer Catherine2
- Mazel V.2
- Most M.2
- Nasr Nesrine2
- Neri Elisabetta2
- Obnorskii V.2
- P Rozet J.2
- P. Germain D.2
- Panchal Mai2
- Pchelintsev A.2
- Pirkl Alexander2
- Raisman-Vozari Rita2
- Reimann C.T.2
- Remillieux J.2
- Roy Sylvaine2
- Rozet J.P.2
- Sablier Michel2
- Saemann-Ischenko G.2
- Salzet M.2
- Schramm Thorsten2
- Schweikert E.A.2
- Sudraud P.2
- Séror Simone J2
- Waast B.2
- Wehbe N.2
- Williams C.T.2
- Čižinauskas Vytis2
- Baratte François2
- Le Douaron Gael2
- Bich C.2
- Litaudon Marc2
- Héron Anne2
- Chaminade P.2
- Chaminade Pierre2
- Wisztorski M.2
- Fournier I.2
- Ferrié Laurent2
- Houël Emeline2
- Desbenoit N.2
- Ouazzani Jamal2
- Benassayag Gérard2
- Coméra Christine2
- Duplais Christophe2
- Roussi Fanny2
- Ollero Mario2
- Zalko Daniel2
- Lazar Adina N2
- Auzeil Nicolas2
- Figadère Bruno2
- Ménez Bénédicte2
- Edelman Aleksander2
- Quinton Loïc2
- Cotte M.2
- Villette Sandrine2
- Al Ali Ahmad1
- Alcami J.1
- Alcami José1
- Ali A.1
- Allegrand Julie1
- Anderson R.1
- Arafah K.1
- Aragoncillo P.1
- Aussel L.1
- Ayciriex S.1
- Ayrault S.1
- Badran Ghidaa1
- Balanzat E.1
- Baratte François1
Auteurs de la structure
Revues
Année de production
Institutions
Laboratoires
Départements
Équipes de recherche
Articles dans une revue163 document
- Caroline Bouvier, Sebastiaan van Nuffel, Alain Brunelle. Tof-SIMS spectra of historical inorganic pigments: Copper-, zinc-, arsenic-, and phosphorus-containing pigments in positive polarity. Surface Science Spectra, 2024, 31 (2), pp.025001. ⟨10.1116/6.0003722⟩. ⟨hal-04637506⟩
- Caroline Bouvier, Sebastiaan van Nuffel, Alain Brunelle. Tof-SIMS spectra of historical inorganic pigments: Copper-, zinc-, arsenic-, and phosphorus-containing pigments in negative polarity. Surface Science Spectra, 2024, 31 (2), pp.025002. ⟨10.1116/6.0003723⟩. ⟨hal-04644238⟩
- Caroline Bouvier, Sebastiaan van Nuffel, Alain Brunelle. ToF-SIMS spectra of historical inorganic pigments: Lead-based pigments in positive polarity. Surface Science Spectra, 2024, 31 (1), pp.015003. ⟨10.1116/6.0003507⟩. ⟨hal-04572572⟩
- Caroline Bouvier, Sebastiaan van Nuffel, Alain Brunelle. ToF-SIMS spectra of historical inorganic pigments: Lead-based pigments in negative polarity. Surface Science Spectra, 2024, 31 (1), pp.015005. ⟨10.1116/6.0003507⟩. ⟨hal-04595993⟩
- Caroline Bouvier, Sebastiaan van Nuffel, Alain Brunelle. Tof-SIMS spectra of historical inorganic pigments: Calcium white pigments in both polarities. Surface Science Spectra, 2024, 31 (1), pp.015007. ⟨10.1116/6.0003592⟩. ⟨hal-04604818⟩
- Laurie Besognet, Baptiste Debret, Julien Siebert, Nicolas Wehr, Alain Brunelle, et al.. Experimental exploration of polycyclic aromatic hydrocarbons stability in subduction zones. Contributions to Mineralogy and Petrology, 2024, 179 (10), pp.89. ⟨10.1007/s00410-024-02163-8⟩. ⟨hal-04693990⟩
- Caroline Bouvier, Sebastiaan van Nuffel, Alain Brunelle. ToF-SIMS spectra of historical inorganic pigments: Natural and synthetic ultramarine blues and smalt in both polarities. Surface Science Spectra, 2024, 31 (1), pp.015006. ⟨10.1116/6.0003640⟩. ⟨hal-04598771⟩
- Raquel Marques, Caroline Bouvier, Marine Cotte, Alain Brunelle, Emeline Pouyet, et al.. Chemical imaging of alligatoring oil paintings. The European Physical Journal Plus, 2023, 138 (9), pp.794. ⟨10.1140/epjp/s13360-023-04330-5⟩. ⟨hal-04207606⟩
- B. Laurent, L. Remusat, J.-C. Viennet, R. Brunetto, L. Binet, et al.. Preservation of the isotope signatures in chondritic IOM during aqueous alteration. Geochemical Perspectives Letters, 2022, 23, pp.28 - 32. ⟨10.7185/geochemlet.2233⟩. ⟨hal-03794414⟩
- Caroline Bouvier, Sebastiaan van Nuffel, Philippe Walter, Alain Brunelle. Time-of-flight secondary ion mass spectrometry imaging in cultural heritage: A focus on old paintings. Journal of Mass Spectrometry, 2022, 57 (1), pp.e4734. ⟨10.1002/jms.4803⟩. ⟨hal-03537014⟩
- Elisabetta Neri, Caroline Bouvier, Laurence de Viguerie, Alain Brunelle, Nesrine Nasr, et al.. Wax finishing in Roman polychrome statuary: Ganosis on the colossal head from Dougga (Tunisia). Journal of Cultural Heritage, 2021, 51, pp.29-36. ⟨10.1016/j.culher.2021.06.013⟩. ⟨hal-03299190⟩
- Caroline Bouvier, Helen Glanville, Laurence de Viguerie, Chiara Merucci, Philippe Walter, et al.. Time-of-Flight Secondary Ion Mass Spectrometry Imaging of Cross Sections from the Bacchanals Paintings of Nicolas Poussin. Analytical Chemistry, 2021, 93 (10), pp.4463-4471. ⟨10.1021/acs.analchem.0c04471⟩. ⟨hal-03171248v2⟩
- Michael Tuck, Landry Blanc, Rita Touti, Nathan Heath Patterson, Sebastiaan van Nuffel, et al.. Multimodal Imaging Based on Vibrational Spectroscopies and Mass Spectrometry Imaging Applied to Biological Tissue: A Multiscale and Multiomics Review. Analytical Chemistry, 2020, ⟨10.1021/acs.analchem.0c04595⟩. ⟨hal-03107524⟩
- Konstantin Nagornov, Anton Kozhinov, Edith Nicol, Oleg Yu. Tsybin, David Touboul, et al.. Narrow Aperture Detection Electrodes ICR Cell with Quadrupolar Ion Detection for FT-ICR MS at the Cyclotron Frequency. Journal of The American Society for Mass Spectrometry, 2020, 31 (11), pp.2258-2269. ⟨10.1021/jasms.0c00221⟩. ⟨hal-02987905⟩
- Sebastiaan van Nuffel, Marceau Quatredeniers, Alexander Pirkl, Julia Zakel, Jean-Pierre Le Caër, et al.. Multimodal Imaging Mass Spectrometry to Identify Markers of Pulmonary Arterial Hypertension in Human Lung Tissue using MALDI-ToF, ToF-SIMS and Hybrid SIMS. Analytical Chemistry, 2020, 92 (17), pp.12079. ⟨10.1021/acs.analchem.0c02815⟩. ⟨hal-02908467⟩
- Imane Abbas, Manale Noun, David Touboul, Dil Sahali, Alain Brunelle, et al.. Kidney Lipidomics by Mass Spectrometry Imaging: A Focus on the Glomerulus. International Journal of Molecular Sciences, 2019, 20 (7), pp.1623. ⟨10.3390/ijms20071623⟩. ⟨hal-02107297⟩
- Tingting Fu, Emeline Houël, Nadine Amusant, David Touboul, Grégory Genta-Jouve, et al.. Biosynthetic investigation of $\gamma$-lactones in Sextonia rubra wood using in situ TOF-SIMS MS/MS imaging to localize and characterize biosynthetic intermediates. Scientific Reports, 2019, 9 (1), pp.1928. ⟨10.1038/s41598-018-37577-5⟩. ⟨hal-02066013⟩
- Bénédicte Ménez, Céline Pisapia, Muriel Andreani, Frederic Jamme, Quentin Vanbellingen, et al.. Abiotic synthesis of amino acids in the recesses of the oceanic lithosphere. Nature, 2018, 564 (7734), pp.59-63. ⟨10.1038/s41586-018-0684-z⟩. ⟨hal-02111683⟩
- Yannicke Dauphin, Alain Brunelle, Kadda Medjoubi, Andrea Somogyi, Jean-Pierre Cuif. The Prismatic Layer of Pinna: A Showcase of Methodological Problems and Preconceived Hypotheses. Minerals, 2018, 8 (9), pp.365. ⟨10.3390/min8090365⟩. ⟨hal-01913674⟩
- Tingting Fu, Nicolas Elie, Alain Brunelle. Radial distribution of wood extractives in European larch Larix decidua by TOF-SIMS imaging. Phytochemistry, 2018, 150, pp.31-39. ⟨10.1016/j.phytochem.2018.02.017⟩. ⟨hal-02111695⟩
- N. Desbenoit, A. Walch, B. Spengler, A. Brunelle, A. Römpp. Correlative mass spectrometry imaging, applying time-of-flight secondary ion mass spectrometry and atmospheric pressure matrix-assisted laser desorption/ionization to a single tissue section. Rapid Communications in Mass Spectrometry, 2018, 32 (2), pp.159-166. ⟨10.1002/rcm.8022⟩. ⟨hal-02111705⟩
- Sebastiaan van Nuffel, Nicolas Elie, Ethan Yang, Julius Nouet, David Touboul, et al.. Insights into the MALDI Process after Matrix Deposition by Sublimation Using 3D ToF-SIMS Imaging. Analytical Chemistry, 2018, 90 (3), pp.1907 - 1914. ⟨10.1021/acs.analchem.7b03993⟩. ⟨hal-01791357⟩
- Tingting Fu, David Touboul, Serge Della-Negra, Emeline Houël, Nadine Amusant, et al.. Tandem MS Imaging and in Situ Characterization of Bioactive Wood Metabolites in Amazonian Tree Species Sextonia rubra. Analytical Chemistry, 2018, 90 (12), pp.7535-7543. ⟨10.1021/acs.analchem.8b01157⟩. ⟨hal-02008867⟩
- Tingting Fu, Serge Della-Negra, David Touboul, Alain Brunelle. Internal Energy Distribution of Secondary Ions Under Argon and Bismuth Cluster Bombardments: “Soft” Versus “Hard” Desorption–Ionization Process. J.Am.Soc.Mass.Spectrom., 2018, 30 (2), pp.321-328. ⟨10.1007/s13361-018-2090-z⟩. ⟨hal-02024237⟩
- Louis-Félix Nothias, Stéphanie Boutet-Mercey, Xavier Cachet, Erick de la Torre, Laurent Laboureur, et al.. Environmentally Friendly Procedure Based on Supercritical Fluid Chromatography and Tandem Mass Spectrometry Molecular Networking for the Discovery of Potent Antiviral Compounds from Euphorbia semiperfoliata. Journal of Natural Products, 2017, 80 (10), pp.2620-2629. ⟨10.1021/acs.jnatprod.7b00113⟩. ⟨hal-03977037⟩
- Vytis Čižinauskas, Nicolas Elie, Alain Brunelle, Vitalis Briedis. Skin Penetration Enhancement by Natural Oils for Dihydroquercetin Delivery. Molecules, 2017, 22 (9), pp.1536. ⟨10.3390/molecules22091536⟩. ⟨hal-03586106⟩
- Tiphaine Péresse, Nicolas Elie, David Touboul, Van-Cuong Pham, Vincent Dumontet, et al.. Dual Beam Depth Profiling and Imaging with Argon and Bismuth Clusters of Prenylated Stilbenes on Glandular Trichomes of Macaranga vedeliana. Analytical Chemistry, 2017, 89 (17), pp.9247-9252. ⟨10.1021/acs.analchem.7b02020⟩. ⟨hal-03176647⟩
- Franck Chiappini, Audrey Coilly, Hanane Kadar, Philippe Gual, Albert Tran, et al.. Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients. Scientific Reports, 2017, 7 (1), pp.46658. ⟨10.1038/srep46658⟩. ⟨hal-03976572⟩
- Vytis Čižinauskas, Nicolas Elie, Alain Brunelle, Vitalis Briedis. Fatty acids penetration into human skin ex vivo : A TOF-SIMS analysis approach. Biointerphases, 2017, 12 (1), pp.011003. ⟨10.1116/1.4977941⟩. ⟨hal-03586110⟩
- Laurent Laboureur, Natacha Bonneau, Pierre Champy, Alain Brunelle, David Touboul. Structural Characterisation of Acetogenins from Annona muricata by Supercritical Fluid Chromatography Coupled to High-Resolution Tandem Mass Spectrometry. Phytochemical Analysis, 2017, 28 (6), pp.512 - 520. ⟨10.1002/pca.2700⟩. ⟨hal-03976580⟩
- Marine Vallet, Quentin P. Vanbellingen, Tingting Fu, Jean-Pierre Le Caer, Serge Della-Negra, et al.. An Integrative Approach to Decipher the Chemical Antagonism between the Competing Endophytes Paraconiothyrium variabile and Bacillus subtilis. Journal of Natural Products, 2017, 80 (11), pp.2863-2873. ⟨10.1021/acs.jnatprod.6b01185⟩. ⟨hal-01998984⟩
- Manale Noun, Elsa van Elslande, David Touboul, Helen Glanville, Spike Bucklow, et al.. High mass and spatial resolution mass spectrometry imaging of Nicolas Poussin painting cross section by cluster TOF-SIMS. Journal of Mass Spectrometry, 2016, 51 (12), pp.1196-1210. ⟨10.1002/jms.3885⟩. ⟨hal-03176641⟩
- N. Bonneau, Isabelle Schmitz-Afonso, A. Brunelle, D. Touboul, P. Champy. Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS. Toxicon, 2016, 118, pp.129-133. ⟨10.1016/j.toxicon.2016.03.015⟩. ⟨hal-02046187⟩
- N. Bonneau, Isabelle Schmitz-Afonso, A. Brunelle, D. Touboul, P. Champy. Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS. Data in Brief, 2016, 7, pp.1633-1638. ⟨10.1016/j.dib.2016.04.067⟩. ⟨hal-02046188⟩
- Quentin P. Vanbellingen, Tingting Fu, Claudia Bich, Nadine Amusant, Didier Stien, et al.. Mapping Dicorynia guianensis Amsh. wood constituents by submicron resolution cluster-TOF-SIMS imaging. Journal of Mass Spectrometry, 2016, 51 (6), pp.412-423. ⟨10.1002/jms.3762⟩. ⟨hal-01532634⟩
- Natacha Bonneau, Isabelle Schmitz-Afonso, Alain Brunelle, David Touboul, Pierre Champy. Method development for quantification of the environmental neurotoxin annonacin in Rat plasma by UPLC–MS/MS and application to a pharmacokinetic study. Journal of Chromatography B Biomedical Sciences and Applications, 2015, 1004, pp.46-52. ⟨10.1016/j.jchromb.2015.09.039⟩. ⟨hal-02367581⟩
- Marie Méjean, Alain Brunelle, David Touboul. Quantification of tocopherols and tocotrienols in soybean oil by supercritical-fluid chromatography coupled to high-resolution mass spectrometry. Analytical and Bioanalytical Chemistry, 2015, 407 (17), pp.5133-5142. ⟨10.1007/s00216-015-8604-7⟩. ⟨hal-01170432⟩
- Quentin P. Vanbellingen, Nicolas Elie, Michael J. Eller, Serge Della-Negra, David Touboul, et al.. Time-of-flight secondary ion mass spectrometry imaging of biological samples with delayed extraction for high mass and high spatial resolutions. Rapid Communications in Mass Spectrometry, 2015, 29 (13), pp.1187-1195. ⟨10.1002/rcm.7210⟩. ⟨hal-01159034⟩
- Claudia Bich, David Touboul, Alain Brunelle. Biomedical studies by TOF-SIMS imaging. Biointerphases, 2015, 10 (1), pp.018901. ⟨10.1116/1.4901511⟩. ⟨hal-01111041⟩
- Andreas Römpp, Jean-Pierre Both, Alain Brunelle, Ron Heeren, Olivier Laprévote, et al.. Mass spectrometry imaging of biological tissue: an approach for multicenter studies. Analytical and Bioanalytical Chemistry, 2015, 407 (8), pp.2329 - 2335. ⟨10.1007/s00216-014-8410-7⟩. ⟨hal-01864902⟩
- Marie Méjean, Alexandre Giuliani, Alain Brunelle, David Touboul. Exploring the peptide fragmentation mechanisms under atmospheric pressure photoionization using tunable VUV synchrotron radiation. International Journal of Mass Spectrometry, 2015, 379, pp.80-86. ⟨10.1016/j.ijms.2014.12.011⟩. ⟨hal-01142939⟩
- Gael Le Douaron, Fanny Schmidt, Majid Amar, Hanane Kadar, Lucila Debortoli, et al.. Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease.. European Journal of Medicinal Chemistry, 2015, 89, pp.467-479. ⟨hal-01111037⟩
- Claudia Bich, David Touboul, Alain Brunelle. Cluster TOF-SIMS imaging as a tool for micrometric histology of lipids in tissue.. Mass Spectrometry Reviews, 2014, 33, pp.442-451. ⟨hal-01075080⟩
- Mathieu Gaudin, Mai Panchal, Sophie Ayciriex, Erwan Werner, Alain Brunelle, et al.. Ultra performance liquid chromatography - mass spectrometry studies of formalin-induced alterations of human brain lipidome. Journal of Mass Spectrometry, 2014, 49 (10), pp.1035 - 1042. ⟨10.1002/jms.3424⟩. ⟨hal-01779050⟩
- Jessica Le Ven, Isabelle Schmitz-Afonso, Guy Lewin, Alain Brunelle, David Touboul, et al.. Identification of the Environmental Neurotoxins Annonaceous Acetogenins in an Annona cherimolia Mill. Alcoholic Beverage Using HPLC-ESI-LTQ-Orbitrap.. Journal of Agricultural and Food Chemistry, 2014, 62 (34), pp.8696-8704. ⟨10.1021/jf501174j⟩. ⟨hal-01059147⟩
- Ahmad Al Ali, David Touboul, Jean-Pierre Le Caër, Isabelle Schmitz-Afonso, Jean-Pierre Flinois, et al.. Optimization and validation of a label-free MRM method for the quantification of cytochrome P450 isoforms in biological samples.. Analytical and Bioanalytical Chemistry, 2014, 406 (20), pp.4861-74. ⟨10.1007/s00216-014-7928-z⟩. ⟨hal-01024697⟩
- Sara Vianello, Francesca Consolaro, Claudia Bich, José-Manuel Cancela, Morgane Roulot, et al.. Low doses of arginine butyrate derivatives improve dystrophic phenotype and restore membrane integrity in DMD models.. FASEB Journal, 2014, 28 (6), pp.2603-2619. ⟨10.1096/fj.13-244798⟩. ⟨hal-01003300⟩
- Nicolas Desbenoit, Emilie Saussereau, Claudia Bich, Matthieu Bourderioux, Janine Fritsch, et al.. Localized lipidomics in cystic fibrosis: TOF-SIMS imaging of lungs from Pseudomonas aeruginosa-infected mice.. International Journal of Biochemistry and Cell Biology, 2014, 52, pp.77-82. ⟨10.1016/j.biocel.2014.01.026⟩. ⟨hal-00995365⟩
- Marie Méjean, Alexandre Giuliani, Alain Brunelle, David Touboul. Letter: Determination of ionization energies of a monoterpene series by atmospheric pressure photoionization using tunable vacuum ultraviolet synchrotron radiation. European Journal of Mass Spectrometry, 2014, 20 (5), pp.403-407. ⟨10.1255/ejms.1291⟩. ⟨hal-01163145⟩
- Hanane Kadar, Gael Le Douaron, Majid Amar, Laurent Ferrié, Bruno Figadère, et al.. MALDI Mass Spectrometry Imaging of 1-Methyl-4-phenylpyridinium (MPP(+)) in Mouse Brain.. Neurotoxicity Research, 2014, 25 (1), pp.135-145. ⟨10.1007/s12640-013-9449-5⟩. ⟨hal-00935375⟩
- Hanane Kadar, Hoa Pham, David Touboul, Alain Brunelle, Olivier Baud. Impact of inhaled nitric oxide on the sulfatide profile of neonatal rat brain studied by TOF-SIMS imaging. International Journal of Molecular Sciences, 2014, 15 (4), pp.5233-5245. ⟨10.3390/ijms15045233⟩. ⟨hal-00966056⟩
- Claudia Bich, Rasmus Havelund, Rudolf Moellers, David Touboul, Felix Kollmer, et al.. Argon cluster ion source evaluation on lipid standards and rat brain tissue samples.. Analytical Chemistry, 2013, 85 (16), pp.7745-52. ⟨10.1021/ac4009513⟩. ⟨hal-00859839⟩
- Nicolas Desbenoit, Isabelle Schmitz-Afonso, Christophe Baudouin, Olivier Laprévote, David Touboul, et al.. Localisation and quantification of benzalkonium chloride in eye tissue by TOF-SIMS imaging and liquid chromatography mass spectrometry.. Analytical and Bioanalytical Chemistry, 2013, 405 (12), pp.4039-49. ⟨10.1007/s00216-013-6811-7⟩. ⟨hal-00816602⟩
- Adina N Lazar, Claudia Bich, Maï Panchal, Nicolas Desbenoit, Vanessa W Petit, et al.. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients.. Acta Neuropathologica, 2013, 125 (1), pp.133-44. ⟨10.1007/s00401-012-1041-1⟩. ⟨hal-00772814⟩
- T. Kezutyte, A. Brunelle, V. Briedis. Studying the penetration of fatty acids into human skin by ex vivo TOF-SIMS imaging. Biointerphases, 2013, 8 (3), pp.1-8. ⟨10.1186/1559-4106-8-3⟩. ⟨hal-00798430⟩
- C. Bich, D. Touboul, A. Brunelle. Study of experimental variability in TOF-SIMS mass spectrometry imaging of biological samples. International Journal of Mass Spectrometry, 2013, 337, pp.43-49. ⟨10.1016/j.ijms.2012.12.010⟩. ⟨hal-00798253⟩
- Adina Lazar, Claudia Bich, Maï Panchal, Nicolas Desbenoit, Vanessa Petit, et al.. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients. Acta Neuropathologica, 2013, 125 (1), pp.133-144. ⟨10.1007/s00401-012-1041-1⟩. ⟨hal-03572637⟩
- M. Mejean, M. Vollmer, A. Brunelle, D. Touboul. Quantification of Retinoid Compounds by Supercritical Fluid Chromatography Coupled to Ultraviolet Diode Array Detection. Chromatographia, 2013, 76 (17-18), pp.1097-1105. ⟨10.1007/s10337-013-2508-5⟩. ⟨hal-00859870⟩
- C. Vercoutère, C. Guérin, L. Crépin, P. Richardin, N. Gandolfo, et al.. Étude pluridisciplinaire du squelette de rhinocéros laineux, Coelodonta antiquitatis (Blumenbach, 1799), de l'Institut de paléontologie humaine (Paris, France). L'anthropologie, 2013, 117, pp.1-47. ⟨10.1016/j.anthro.2013.01.003⟩. ⟨hal-00807922⟩
- Carole Vercoutère, Claude Guérin, Laurent Crépin, Pascale Richardin, Nathalie Gandolfo, et al.. Étude pluridisciplinaire du squelette de rhinocéros laineux, Coelodonta antiquitatis (Blumenbach, 1799), de l’Institut de paléontologie humaine (Paris, France). L'anthropologie, 2013, 117 (1), pp.1-47. ⟨10.1016/j.anthro.2013.01.003⟩. ⟨hal-03151558⟩
- C. Bich, S. Vianello, V. Guérineau, D. Touboul, S. de La Porte, et al.. Compatibility between TOF-SIMS lipid imaging and histological staining on a rat brain section. Surface and Interface Analysis, 2013, 45 (1), pp.260-263. ⟨10.1002/sia.4846⟩. ⟨hal-00778696⟩
- Alexandre Seyer, Michela Cantiello, Justine Bertrand-Michel, Véronique Roques, Michel Nauze, et al.. Lipidomic and Spatio-Temporal Imaging of Fat by Mass Spectrometry in Mice Duodenum during Lipid Digestion.. PLoS ONE, 2013, 8 (4), pp.e58224. ⟨10.1371/journal.pone.0058224⟩. ⟨hal-00816571⟩
- Jessica Le Ven, Isabelle Schmitz-Afonso, Guy Lewin, Olivier Laprévote, Alain Brunelle, et al.. Comprehensive characterization of Annonaceous acetogenins within a complex extract by HPLC-ESI-LTQ-Orbitrap® using post-column lithium infusion.. Journal of Mass Spectrometry, 2012, 47 (11), pp.1500-9. ⟨10.1002/jms.3092⟩. ⟨hal-00758261⟩
- Mathieu Gaudin, Maï Panchal, Nicolas Auzeil, Charles Duyckaerts, Alain Brunelle, et al.. Choline-containing phospholipids in microdissected human Alzheimer's disease brain senile plaque versus neuropil.. Bioanalysis, 2012, 4 (17), pp.2153-5159. ⟨10.4155/bio.12.189⟩. ⟨hal-00742423⟩
- Thorsten Schramm, Alfons Hester, Ivo Klinkert, Jean-Pierre Both, Ron M A Heeren, et al.. imzML - A common data format for the flexible exchange and processing of mass spectrometry imaging data.. Journal of Proteomics, 2012, 75 (16), pp.5106-10. ⟨10.1016/j.jprot.2012.07.026⟩. ⟨hal-00741330⟩
- Julie Allegrand, David Touboul, Alexandre Giuliani, Alain Brunelle, Olivier Laprévote. Atmospheric pressure photoionization mass spectrometry of guanine using tunable synchrotron VUV radiation. International Journal of Mass Spectrometry, 2012, 321-322, pp.14-18. ⟨10.1016/j.ijms.2012.05.009⟩. ⟨hal-00740856⟩
- Mathieu Gaudin, Laurent Imbert, Danielle Libong, Pierre Chaminade, Alain Brunelle, et al.. Atmospheric pressure photoionization as a powerful tool for large-scale lipidomic studies.. Journal of The American Society for Mass Spectrometry, 2012, 23 (5), pp.869-79. ⟨10.1007/s13361-012-0341-y⟩. ⟨hal-00690894⟩
- Christopher D Cerruti, Farida Benabdellah, Olivier Laprévote, David Touboul, Alain Brunelle. MALDI imaging and structural analysis of rat brain lipid negative ions with 9-aminoacridine matrix.. Analytical Chemistry, 2012, 84 (5), pp.2164-71. ⟨10.1021/ac2025317⟩. ⟨hal-00690891⟩
- Sophie Cersoy, Pascale Richardin, Philippe Walter, Alain Brunelle. Cluster TOF-SIMS imaging of human skin remains: analysis of a South-Andean mummy sample.. Journal of Mass Spectrometry, 2012, 47 (3), pp.338-46. ⟨10.1002/jms.2979⟩. ⟨hal-00690478⟩
- F. Brignole-Baudouin, N. Desbenoit, G. Hamm, H. Liang, J. P. Both, et al.. A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits. PLoS ONE, 2012, 7 (11), pp.e50180. ⟨10.1371/journal.pone.0050180⟩. ⟨hal-00764054⟩
- Pascale Richardin, Vincent Mazel, Philippe Walter, Olivier Laprévote, Alain Brunelle. Identification of Different Copper Green Pigments in Renaissance Paintings by Cluster-TOF-SIMS Imaging Analysis.. Journal of The American Society for Mass Spectrometry, 2011, 22 (10), pp.1729-36. ⟨10.1007/s13361-011-0171-3⟩. ⟨hal-00634147⟩
- David Touboul, Olivier Laprévote, Alain Brunelle. Micrometric molecular histology of lipids by mass spectrometry imaging.. Current Opinion in Chemical Biology, 2011, 15 (5), pp.725-732. ⟨10.1016/j.cbpa.2011.04.017⟩. ⟨hal-00634156⟩
- Venant Nihorimbere, Hélène Cawoy, Alexandre Seyer, Alain Brunelle, Philippe Thonart, et al.. Impact of rhizosphere factors on cyclic lipopeptide signature from the plant beneficial strain Bacillus amyloliquefaciens S499.. FEMS Microbiology Ecology, 2011, 79 (1), pp.176-191. ⟨10.1111/j.1574-6941.2011.01208.x⟩. ⟨hal-00653939⟩
- Christopher D Cerruti, David Touboul, Vincent Guérineau, Vanessa W Petit, Olivier Laprévote, et al.. MALDI imaging mass spectrometry of lipids by adding lithium salts to the matrix solution.. Analytical and Bioanalytical Chemistry, 2011, 401 (1), pp.75-87. ⟨10.1007/s00216-011-4814-9⟩. ⟨hal-00606476⟩
- Jana Sanyova, Sophie Cersoy, Pascale Richardin, Olivier Laprévote, Philippe Walter, et al.. Unexpected Materials in a Rembrandt Painting Characterized by High Spatial Resolution Cluster-TOF-SIMS Imaging.. Analytical Chemistry, 2011, 83 (3), pp.753-760. ⟨10.1021/ac1017748⟩. ⟨hal-00572516⟩
- S. Ayciriex, D. Touboul, A. Brunelle, O. Laprévote. Time-of-flight secondary ion mass spectrometry: a novel tool for lipid imaging. Clin Lipidol, 2011, 6 (4), pp.437-445. ⟨10.2217/CLP.11.31⟩. ⟨hal-00673010⟩
- C. Meriaux, K. Arafah, A. Tasiemski, M. Wisztorski, J. Bruand, et al.. Multiple Changes in Peptide and Lipid Expression Associated with Regeneration in the Nervous System of the Medicinal Leech. PLoS ONE, 2011, 6 (4), pp.1-20. ⟨10.1371/journal.pone.0018359⟩. ⟨hal-00589141⟩
- B. Farre, A. Brunelle, O. Laprévote, J.P. Cuif, C.T. Williams, et al.. Shell layers of the black-lip pearl oyster Pinctada margaritifera : matching microstructure and composition. Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology, 2011, 159 ((3):), pp.131-139. ⟨10.1016/j.cbpb.2011.03.001⟩. ⟨hal-00599661⟩
- David Touboul, Alain Brunelle, Olivier Laprévote. Mass spectrometry imaging: Towards a lipid microscope?. Biochimie, 2011, 93 (1), pp.113-9. ⟨10.1016/j.biochi.2010.05.013⟩. ⟨hal-00581325⟩
- Alexandre Seyer, Anne Riu, Laurent Debrauwer, Nathalie Bourgès-Abella, Alain Brunelle, et al.. Time-of-Flight Secondary Ion Mass Spectrometry Imaging Demonstrates the Specific Localization of Deca-Bromo-Diphenyl-Ether Residues in the Ovaries and Adrenal Glands of Exposed Rats.. Journal of The American Society for Mass Spectrometry, 2010, 21 (11), pp.1836-45. ⟨10.1016/j.jasms.2010.06.019⟩. ⟨hal-00530043⟩
- Marc Brulet, Alexandre Seyer, Aleksander Edelman, Alain Brunelle, Janine Fritsch, et al.. Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice.. Journal of Lipid Research, 2010, 51 (10), pp.3034-45. ⟨10.1194/jlr.M008870⟩. ⟨hal-00522087⟩
- Vincent Mazel, Pascale Richardin, David Touboul, Alain Brunelle, Caroline Richard, et al.. Animal urine as painting materials in African rock art revealed by cluster ToF-SIMS mass spectrometry imaging.. Journal of Mass Spectrometry, 2010, 45 (8), pp.944-50. ⟨10.1002/jms.1789⟩. ⟨hal-00522056⟩
- Alexandre Seyer, Jacques Einhorn, Alain Brunelle, Olivier Laprévote. Localization of Flavonoids in Seeds by Cluster Time-of-Flight Secondary Ion Mass Spectrometry Imaging.. Analytical Chemistry, 2010, 82 (6), pp.2326-33. ⟨10.1021/ac902528t⟩. ⟨hal-00464263⟩
- Farida Benabdellah, Alexandre Seyer, Loïc Quinton, David Touboul, Alain Brunelle, et al.. Mass spectrometry imaging of rat brain sections: nanomolar sensitivity with MALDI versus nanometer resolution by TOF-SIMS.. Analytical and Bioanalytical Chemistry, 2010, 396 (1), pp.151-62. ⟨10.1007/s00216-009-3031-2⟩. ⟨hal-00450885⟩
- N. Wehbe, M. Fallavier, S. Della Negra, J. Depauw, A. Brunelle, et al.. Cluster size and velocity dependences of sputtering and secondary ion emission under gold cluster impact. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2010, 268, pp.2596-2602. ⟨10.1016/j.nimb.2010.05.105⟩. ⟨in2p3-00520215⟩
- A. Brunelle, O. Laprévote. MALDI Imaging Mass Spectrometry. Electrospray and MALDI Mass Spectrometry, 2010, chapitre 8, pp.245-261. ⟨hal-00493933⟩
- V. W. Petit, M. Réfrégiers, C. Guettier, F. Jamme, K. Sebanayakam, et al.. Multimodal Spectroscopy Combining Time-of-Flight-Secondary Ion Mass Spectrometry, Synchrotron-FT-IR, and Synchrotron-UV Microspectroscopies on the Same Tissue Section. Analytical Chemistry, 2010, 82 (9), pp.3963-3968. ⟨10.1021/ac100581y⟩. ⟨hal-00480649⟩
- Y. Dauphin, A. Brunelle, M. Cotte, J. P. Cuif, B. Farre, et al.. A layered structure in the organic envelopes of the prismatic layer of the shell of the pearl oyster Pinctada margaritifera (mollusca, bivalvia). Microscopy and Microanalysis, 2010, 16, pp.91-98. ⟨10.1017/S1431927609991115⟩. ⟨hal-00451111⟩
- François Le Naour, Catherine Guettier, Alain Brunelle, Olivier Laprévote, Paul Dumas. [Synchrotron SOLEIL radiation reveals discrete biochemical changes in human steatosis]. Médecine/Sciences, 2009, 25 (11), pp.987-90. ⟨10.1051/medsci/20092511987⟩. ⟨hal-00459222⟩
- Farida Benabdellah, Hua Yu, Alain Brunelle, Olivier Laprévote, Sabine de La Porte. MALDI reveals membrane lipid profile reversion in MDX mice.. Neurobiology of Disease, 2009, 36 (2), pp.252-8. ⟨10.1016/j.nbd.2009.07.013⟩. ⟨hal-00408301⟩
- Farida Benabdellah, David Touboul, Alain Brunelle, Olivier Laprévote. In situ primary metabolites localization on a rat brain section by chemical mass spectrometry imaging.. Analytical Chemistry, 2009, 81 (13), pp.5557-60. ⟨10.1021/ac9005364⟩. ⟨hal-00401566⟩
- Delphine Debois, Marie-Pierre Bralet, François Le Naour, Alain Brunelle, Olivier Laprévote. In situ lipidomic analysis of nonalcoholic fatty liver by cluster TOF-SIMS imaging.. Analytical Chemistry, 2009, 81 (8), pp.2823-31. ⟨10.1021/ac900045m⟩. ⟨hal-00377469⟩
- Delphine Debois, Kassem Hamze, Vincent Guérineau, Jean-Pierre Le Caër, I Barry Holland, et al.. In situ localisation and quantification of surfactins in a Bacillus subtilis swarming community by imaging mass spectrometry.. Proteomics, 2009, 9 (1), pp.210. ⟨10.1002/pmic.200890094⟩. ⟨hal-00353383⟩
- F. Le Naour, M. P. Bralet, D. Debois, C. Sandt, C. Guettier, et al.. Chemical imaging on liver steatosis using synchrotron infrared and ToF-SIMS microspectroscopies. PLoS ONE, 2009, 4 (10), pp.e7408-. ⟨10.1371/journal.pone.0007408⟩. ⟨hal-00424260⟩
- A. Seyer, L. Riu, L. Debrauwer, O. Laprévote, N. Bourges, et al.. TOF-SIMS MASS SPECTROMETRY IMAGING DEMONSTRATES A SELECTIVE TROPISM OF BDE-209 RESIDUES LOCATION IN TARGET TISSUES OF RATS. Organohalogen Compounds, 2009, 71, pp.961-965. ⟨hal-00770852⟩
- F. Le Naour, C. Guettier, A. Brunelle, O. Laprévote, P. Dumas. Imagerie chimique de la stéatose hépatique. Médecine/Sciences, 2009, 25 (11), pp.987-990. ⟨hal-00439821⟩
- Alain Brunelle, Olivier Laprévote. Lipid imaging with cluster time-of-flight secondary ion mass spectrometry.. Analytical and Bioanalytical Chemistry, 2009, 393 (1), pp.31-5. ⟨10.1007/s00216-008-2367-3⟩. ⟨hal-00353508⟩
- Delphine Debois, Kassem Hamze, Vincent Guérineau, Jean-Pierre Le Caër, I Barry Holland, et al.. In situ localisation and quantification of surfactins in a Bacillus subtilis swarming community by imaging mass spectrometry.. Proteomics, 2008, 8 (18), pp.3682-91. ⟨10.1002/pmic.200701025⟩. ⟨hal-00326299⟩
- Gabriel Mazzucchelli, Nicolas Cellier, Vakhtang Mshviladzade, Riad Elias, Yong-Ho Shim, et al.. Pores Formation on Cell Membranes by Hederacolchiside A1 Leads to a Rapid Release of Proteins for Cytosolic Subproteome Analysis.. Journal of Proteome Research, 2008, 7 (4), pp.1683-1692. ⟨10.1021/pr7006973⟩. ⟨hal-00275499⟩
- Nora Tahallah, Alain Brunelle, Sabine de La Porte, Olivier Laprévote. Lipid mapping in human dystrophic muscle by cluster-time-of-flight secondary ion mass spectrometry imaging.. Journal of Lipid Research, 2008, 49 (2), pp.438-54. ⟨10.1194/jlr.M700421-JLR200⟩. ⟨hal-00189846⟩
- Mitchell James Power, J. Marlon, N. Ortiz, P. Bartlein, S. Harrison, et al.. Changes in fire regime since the Last Glacial Maximum: an assessment based on a global synthesis and analysis of charcoal data. Climate Dynamics, 2008, 30 (7-8), pp.887-907. ⟨hal-00436657⟩
- V. Mazel, P. Richardin, D. Debois, D. Touboul, M. Cotte, et al.. The patinas of the Dogon-Tellem statuary : a new vision through physico-chemical analyses. Journal of Cultural Heritage, 2008, 9 (3), pp.347-353. ⟨10.1016/j.culher.2007.11.003⟩. ⟨hal-00326957⟩
- Vincent Mazel, Pascale Richardin, Delphine Debois, David Touboul, Marine Cotte, et al.. Identification of Ritual Blood in African Artifacts Using TOF-SIMS and Synchrotron Radiation Microspectroscopies.. Analytical Chemistry, 2007, 79 (24), pp.9253-9260. ⟨10.1021/ac070993k⟩. ⟨hal-00198527⟩
- David Touboul, Alain Brunelle, Olivier Laprévote. Characterization of alpha-parvalbumin on muscle tissue sections by in situ calcium attachment.. Rapid Communications in Mass Spectrometry, 2007, 21 (22), pp.3756-3758. ⟨10.1002/rcm.3246⟩. ⟨hal-00185601⟩
- S. Mas, D. Touboul, A. Brunelle, P. Aragoncillo, J. Egido, et al.. Lipid cartography of atherosclerotic plaque by cluster-TOF-SIMS Imaging.. Analyst, 2007, 132, pp.24-26. ⟨10.1039/b614619h⟩. ⟨hal-00124060⟩
- D. Debois, A. Brunelle, O. Laprévote. Attempts for molecular depth profiling directly on a rat brain tissue section using fullerene and bismuth cluster ion beams.. International Journal of Mass Spectrometry, 2007, 260(, pp.115-120. ⟨10.1016/j.ijms.2006.09.026⟩. ⟨hal-00124043⟩
- D. Touboul, A. Brunelle, D. P. Germain, O. Laprévote. A new imagine technique as a diagnostic tool : mass spectrometry. La Presse medicale, 2007, 36 (1), pp.S82-S87. ⟨hal-00146315⟩
- A. Brunelle, O. Laprévote. Recent advances in biological tissue imaging wiht time-of-flight secondary ion mass spectrometry : polyatomic ion sources, sample preparation, and applications. Curr Pharm Design, 2007, 13 (32), pp.3335-3343. ⟨hal-00185628⟩
- D. Touboul, Sylvaine Roy, D. P. Germain, P. Chaminade, A. Brunelle, et al.. MALDI-TOF and cluster-TOF-SIMS imaging of Fabry disease biomarkers.. International Journal of Mass Spectrometry, 2007, 260(2-3), pp.158-165. ⟨10.1016/j.ijms.2006.09.027⟩. ⟨hal-00124036⟩
- Sylvaine Roy, D. Touboul, A. Brunelle, D.P. Germain, P. Prognon, et al.. Imagerie Biologique Imagerie par spectrométrie de masse : un nouvel outil pour l'analyse de biopsies cutanées. Application à la maladie de Fabry.. Annales Pharmaceutiques Françaises, 2006, 64(, pp.328-334. ⟨hal-00115180⟩
- A. Brunelle, D. Touboul, O. Laprévote. Nouvelles perspectives en biologie avec l'imagerie moléculaire par spectrométrie de masse. Spectra Analyse, 2006, 250(, pp.20-26. ⟨hal-00091536⟩
- S. Bouneau, A. Brunelle, S. Della-Negra, J. Depauw, D. Jacquet, et al.. Energy loss and angular distributions of gold cluster constituents. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2006, 251, pp.383-389. ⟨10.1016/j.nimb.2006.08.001⟩. ⟨in2p3-00113792⟩
- V. Mazel, P. Richardin, D. Touboul, A. Brunelle, P. Walter, et al.. Chemical imaging techniques for the analysis of complex mixtures : new application to the characterization of ritual matters on african wooden statuettes. Analytica Chimica Acta, 2006, 570(1), pp.34-40. ⟨10.1016/j.aca.2006.03.111⟩. ⟨hal-00077572⟩
- David Touboul, Alain Brunelle, Olivier Laprévote. Structural analysis of secondary ions by post-source decay in time-of-flight secondary ion mass spectrometry. Rapid Communications in Mass Spectrometry, 2006, 20, pp.703-709. ⟨10.1002/rcm.2362⟩. ⟨hal-00018296⟩
- David Touboul, Felix Kollmer, Ewald Niehuis, Alain Brunelle, Olivier Laprévote. Improvement of biological time-of-flight-secondary ion mass spectrometry imaging with a bismuth cluster ion source. Journal of The American Society for Mass Spectrometry, 2005, 16 (10), pp.1608-1618. ⟨10.1016/j.jasms.2005.06.005⟩. ⟨hal-03985979⟩
- Sandrine Roy, David Touboul, Alain Brunelle, Dominique P. Germain, Olivier Laprévote, et al.. Apport de l'imagerie par spectrométrie de masse pour l'analyse directe du globotriaosylcéramide et du galabiosylcéramide tissulaires. Médecine/Sciences, 2005, 21, N° spécial, pp.55-56. ⟨hal-00017264⟩
- Alain Brunelle, David Touboul, Olivier Laprévote. Biological tissue imaging with time-of-flight secondary ion mass spectrometry and cluster ion sources. Journal of Mass Spectrometry, 2005, 40 (8), pp.985-999. ⟨10.1002/jms.902⟩. ⟨hal-03976550⟩
- David Touboul, Alain Brunelle, Frédéric Halgand, Sabine de La Porte, Olivier Laprévote. Lipid imaging by gold cluster time-of-flight secondary ion mass spectrometry : application to Duchenne muscular dystrophy. Journal of Lipid Research, 2005, 46 (7), pp.1388-1395. ⟨10.1194/jlr.M500058-JLR200⟩. ⟨hal-00101131⟩
- David Touboul, Fréderic Halgand, Alain Brunelle, Reinhard Kersting, Elke Tallarek, et al.. Tissue Molecular Ion Imaging by Gold Cluster Ion Bombardment. Analytical Chemistry, 2004, 76 (6), pp.1550-1559. ⟨10.1021/ac035243z⟩. ⟨hal-03976543⟩
- A. Brunelle, S. Della-Negra. Trends to a semi-empirical model for cluster induced metal sputtering. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2004, 222, pp.68-74. ⟨in2p3-00021962⟩
- David Touboul, Hélène Piednoël, Vincent Voisin, Sabine de La Porte, Alain Brunelle, et al.. Changes of phospholipid composition within the dystrophic muscle by matrix-assisted laser desorption/ionization mass spectrometry and mass spectrometry imaging.. European Journal of Mass Spectrometry, 2004, 10 (5), pp.657-664. ⟨10.1255/ejms.671⟩. ⟨hal-00139821⟩
- I. Baranov, A. Brunelle, S. Della-Negra, D. Jacquet, S. Kirillov, et al.. Desorption of metal nanoclusters (2-40 nm) from nanodispersed targets of gold by swift heavy cluster (C$_8$, 20 MeV) and atomic (fission fragments) projectiles. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2002, 187, pp.451-458. ⟨in2p3-00011461⟩
- S. Bouneau, A. Brunelle, S. Della-Negra, J. Depauw, D. Jacquet, et al.. Very large gold and silver sputtering yields induced by keV to MeV energy Au$_n$ clusters (n = 1-13). Physical Review B: Condensed Matter and Materials Physics (1998-2015), 2002, 65, pp.144106-1-144106-8. ⟨in2p3-00011005⟩
- P. Chevallier, J-C. Soutif, J-C. Brosse, A. Brunelle. Poly(amide ester)s from 2,6-pyridinedicarboxylic acid and ethanolamine derivatives: identification of macrocycles by matrix-assisted laser - desorption/ionization mass spectrometry. Rapid Communications in Mass Spectrometry, 2002, 16, pp.1476-1484. ⟨in2p3-00019918⟩
- A. Brunelle, S. Della-Negra, J. Depauw, D. Jacquet, Y. Le Beyec, et al.. Enhanced secondary-ion emission under gold-cluster bombardment with energies from keV to MeV per atom. Physical Review A : Atomic, molecular, and optical physics [1990-2015], 2001, 63, pp.022902-1-022902-10. ⟨in2p3-00008373⟩
- M. Seidl, H. Voit, S. Bouneau, A. Brunelle, S. Della-Negra, et al.. MeV carbon cluster-induced pulse height defect in a surface barrier detector. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2001, 183, pp.502-508. ⟨in2p3-00019687⟩
- S. Bouffard, C. Leroy, S. Della-Negra, A. Brunelle, J.M. Costantini. Damage production yield by electron excitation in mica for ion and cluster irradiations. Philosophical Magazine a, 2001, 81, pp.2841-2854. ⟨in2p3-00010692⟩
- M. Most, K. Wien, A. Brunelle, S. Della Negra, J. Depauw, et al.. H$^+$ emission by MeV-ion impact: charge state dependence of energy and angular distributions. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2000, 168, pp.203-214. ⟨in2p3-00004738⟩
- D. Karibian, A. Brunelle, L. Aussel, M. Caroff. $^{Cf}$252-plasma desorption mass spectrometry of unmodified lipid A:Fragmentation patterns and localization of fatty acids. Rapid Communications in Mass Spectrometry, 1999, 13, pp.2252-2259. ⟨in2p3-00015696⟩
- A. Brunelle, S. Della-Negra, J. Depauw, D. Jacquet, Y. Le Beyec, et al.. Reduced charge state of MeV carbon cluster constituents exiting thin carbon foils. Physical Review A : Atomic, molecular, and optical physics [1990-2015], 1999, 59, pp.4456-4460. ⟨in2p3-00002350⟩
- F. Dubois, R. Knochenmuss, R. Zenobi, A. Brunelle, C. Deprun, et al.. A comparison between ion-to-photon and microchannel plate detectors. Rapid Communications in Mass Spectrometry, 1999, 13, pp.786-791. ⟨in2p3-00014852⟩
- H. Lavanant, A. Brunelle, Y. Hoppilliar. Kinetic energies of histidine/Cu+ complexes desorbed by MeV particle bombardment. Rapid Communications in Mass Spectrometry, 1998, 12, pp.1137-1142. ⟨in2p3-00014866⟩
- H.H. Andersen, A. Brunelle, S. Della-Negra, J. Depauw, D. Jacquet, et al.. Giant Metal Sputtering Yields Induced by 20-5000 keV/atom Gold Clusters. Physical Review Letters, 1998, 80, pp.5433-5436. ⟨in2p3-00000032⟩
- A. Brunelle, S. Della-Negra, C. Deprun, J. Depauw, P. Hakansson, et al.. High desorption-ionization yields of large biomolecules induced by fast C$_{60}$ projectiles. International journal of mass spectrometry and ion processes, 1997, 164, pp.193-200. ⟨in2p3-00004012⟩
- A. Brunelle, S. Della-Negra, J. Depauw, D. Jacquet, Y. Le Beyec, et al.. Collisions of fast clusters with solids and related phenomena. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1997, 125, pp.207-213. ⟨in2p3-00007621⟩
- K. Wohrer, M. Chabot, J.P. Rozet, D. Gardes, Dominique Vernhet, et al.. Capture and ionization cross sections in 10 MeV C$^+_5$ cluster-helium collisions. Physica Scripta, 1997, T73, pp.284-285. ⟨in2p3-00014442⟩
- A. Brunelle, P. Chaurand, S. Della Negra, Y. Le Beyec, E. Parilis. Secondary electron emission yields from a CsI surface under impacts of large molecules at low velocities (5 x 10$^3 -7$ x 10$^4$). Rapid Communications in Mass Spectrometry, 1997, 11, pp.353. ⟨in2p3-00018237⟩
- D.D.N. Barlo Daya, C.T. Reimann, P. Hakansson, B.U.R. Sundqvist, A. Brunelle, et al.. Crater formation due to grazing incidence $c_60$ cluster ion impacts on mica : a tapping-mode scanning force microscopy study. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1997, 124, pp.484-489. ⟨in2p3-00001085⟩
- M. Chabot, K. Wohrer, J-P. Rozet, D. Gardes, Dominique Vernhet, et al.. Fragmentation patterns of ionized C$_5^ {Q+}$ clusters (Q=1 $\rightarrow$4). Physica Scripta, 1997, T73, pp.282-283. ⟨in2p3-00004013⟩
- A. Brunelle, S. Della Negra, Y. Le Beyec. Backward emission of light ions from polyatomic projectiles during keV energy bombardment of solid surfaces. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1997, 132, pp.718-723. ⟨in2p3-00003981⟩
- K. Wohrer, M. Chabot, J.P. Rozet, D. Gardes, Dominique Vernhet, et al.. Swift cluster-atom collisions: experiment and model calculations. Journal of Physics B: Atomic, Molecular and Optical Physics, 1996, 29, pp.L755-L761. ⟨in2p3-00015321⟩
- D. Laplaze, P. Bernier, G. Flamant, M. Lebrun, A. Brunelle, et al.. Solar energy: application of the production of fullerenes. Journal of Physics B: Atomic, Molecular and Optical Physics, 1996, 29, pp.4943. ⟨in2p3-00018235⟩
- D. Laplaze, P. Bernier, G. Flamant, M. Lebrun, A. Brunelle, et al.. Preparation of fullerenes using a solar furnace. Synthetic Metals, 1996, 77, pp.67-71. ⟨in2p3-00018233⟩
- K. Baudin, A. Brunelle, S. Della Negra, D. Jacquet, P. Hakansson, et al.. Sputtering of large size clusters from solids bombarded by high energy cluster ions and fullerenes. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1996, 112, pp.59-63. ⟨in2p3-00018234⟩
- K. Baudin, A. Brunelle, S. Della-Negra, J. Depauw, Y. Le Beyec, et al.. Sublinear effect in electron emission from solids bombarded with swift gold clusters. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1996, 117, pp.47-54. ⟨in2p3-00000953⟩
- C. Tomaschko, M. Schurr, R. Berger, G. Saemann-Ischenko, H. Voit, et al.. Visualisation of craters in a Langmuir-Blodgett film from the impact of 23 MeV C$_{60}^{1+}$. Rapid Communications in Mass Spectrometry, 1996, 9, pp.924. ⟨in2p3-00018236⟩
- C. Tomaschko, C. Schoppmann, M. Kraus, K. Kragler, G. Kreiselmeyer, et al.. MeV cluster ion induced defect production in high T$_c$ superconductors. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1996, 117, pp.90-94. ⟨in2p3-00001918⟩
- M. Beranger, P. Thevenard, R. Brenier, B. Canut, S.M.M. Ramos, et al.. Ion-beam mixing induced by atomic and cluster bonbardment in the electronic stopping-power regime. Physical Review B: Condensed Matter and Materials Physics (1998-2015), 1996, 53, pp.14773-14781. ⟨in2p3-00002013⟩
- H. Dammak, A. Dunlop, D. Lesueur, A. Brunelle, S. Della Negra, et al.. Tracks in metals by MeV fullerenes. Physical Review Letters, 1995, 74, pp.1135-1138. ⟨in2p3-00018230⟩
- A. Hallen, P. Haakansson, J. Olsson, A. Brunelle, S. Della-Negra, et al.. Vacancy related defect profiles in MeV cluster-ion irradiated silicon. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1995, 106, pp.233-236. ⟨in2p3-00014513⟩
- D.D.N. Barlo Daya, A. Hallen, J. Eriksson, J. Kopnicky, R. Papaleo, et al.. Radiation damage features on mica and L-valine probed by scanning force microscopy. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1995, 106, pp.38-42. ⟨in2p3-00014516⟩
- D. Laplaze, P. Bernier, L. Barbedette, J-M. Lambert, G. Flamant, et al.. Production de fullerenes a partir de l'energie solaire: l'experience d'Odeillo. Comptes Rendus de l'Academie des Sciences Serie II, 1994, 318, pp.733-738. ⟨in2p3-00007256⟩
- K. Baudin, A. Brunelle, M. Chabot, S. Della-Negra, J. Depauw, et al.. Energy loss by mev carbon clusters and fullerene ions in solids. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1994, 94, pp.341-344. ⟨in2p3-00003520⟩
- K. Boussofiane-Baudin, A. Brunelle, P. Chaurand, J. Depauw, S. Della Negra, et al.. High energy carbon cluster beams. International journal of mass spectrometry and ion processes, 1993, 130, pp.73-82. ⟨in2p3-00018231⟩
- S. Della-Negra, A. Brunelle, Y. Le Beyec, J.M. Curaudeau, J.P. Mouffron, et al.. Acceleration of $C^{n+}_{60}$ molecules to high energy. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1993, 74, pp.453-456. ⟨in2p3-00002818⟩
- A. Brunelle, P. Chaurand, S. Della Negra, Y. Le Beyec, G.B. Baptista. Surface secondary electron and secondary ion emission induced by large molecular ion impacts. International journal of mass spectrometry and ion processes, 1993, 126, pp.65-73. ⟨in2p3-00018232⟩
- C. Schoppmann, P. Wohlfart, D. Brandl, M. Sauer, C. Tomaschko, et al.. Acceleration of Au$_n$ clusters to MeV energies. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1993, 82, pp.156-160. ⟨in2p3-00014687⟩
- A. Brunelle, S. Della-Negra, Y. Le Beyec. Progres des temps de vol. Analusis, 1992, 20, pp.417-420. ⟨in2p3-00004643⟩
- A. Brunelle, S. Della-Negra, J. Depauw, H. Joret, Y. Le Beyec. Time-of-flight mass spectrometry with a compact two-stage electrostatic mirror : metastable ion studies with high mass resolution and ion emission from thick insulators. Rapid Communications in Mass Spectrometry, 1991, 5, pp.40-43. ⟨in2p3-00016306⟩
- G.B. Baptista, A. Brunelle, P. Chaurand, S. Della-Negra, Y. Le Beyec. Ion counting and ion intensity measurements in time-of-flight mass spectrometry - Application to matrix-assisted laser desorption. Rapid Communications in Mass Spectrometry, 1991, 5, pp.632-637. ⟨in2p3-00016152⟩
- M. Benguerba, A. Brunelle, S. Della-Negra, J. Depauw, H. Joret, et al.. Impact of slow gold clusters on various solids: nonlinear effects in secondary ion emission. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1991, 62, pp.8-22. ⟨in2p3-00016202⟩
- A. Brunelle, S. Della-Negra, J. Depauw, H. Joret, Y. Le Beyec. A simple way to study secondary ion emission by heavy multicharged ions at medium energy (=115 KeV). Application to hydrogen ion emission. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1989, 43, pp.586-588. ⟨in2p3-00016346⟩
- A. Brunelle, S. Della-Negra, J. Depauw, H. Joret, Y. Le Beyec, et al.. New measurements of the mean equilibrium charge of MeV/u heavy ions inside the cold matter with the H$^+$ emission probe. Radiation Effects and Defects in Solids, 1989, 110, pp.85-88. ⟨in2p3-00016308⟩
Communications dans un congrès47 document
- Aline Cournut, Tomas Herrera-Durigneux, Quentin Vanbellingen, Anais Demaye, Julia Kokesh-Himmelreich, et al.. TOF-SIMS imaging analysis to determine Cognac barrels oak wood interaction with specific fungi. SIMS XXIV 24th International Conference on Secondary Ion Mass Spectrometry, Sep 2024, La Rochelle (Charente-Maritime, Nouvelle-Aquitaine), France. ⟨hal-04687254⟩
- Manale Noun, Razane El Annan, Alain Brunelle, Jean-Paul Salvetat, Sandrine Villette, et al.. Fine particulate matter effects on human bronchial epithelial cells using 2D and 3D ToF-SIMS imaging. SIMS XXIV 24th International Conference on Secondary Ion Mass Spectrometry, Sep 2024, La Rochelle, France. ⟨hal-04699888⟩
- Aline Cournut, Quentin Vanbellingen, Anais Demaye, Julia Kokesch-Himmelreich, Andreas Römpp, et al.. Multimodal analysis of oak wood metabolites for a comprehensive understanding of the ageing process in French typical spirits barrels. International Congress on Natural Products Research, Jul 2024, Krakow (Cracovie), Poland. ⟨hal-04651739⟩
- Aline Cournut, Tomas Herrera-Durigneux, Philippe Walter, David Touboul, Andreas Römpp, et al.. TOF-SIMS imaging analysis of fungi present in Cognac cellars. Journées Scientifiques Annuelles du GDR-MSI Imagerie par Spectrométrie de Masse, GDR-MSI, Jun 2024, Strasbourg, France. ⟨hal-04631347⟩
- Gauthier Rosé, Emeline Pouyet, Leila Sauvage, Lucile Brunel-Duverger, Laurence de Viguerie, et al.. TOF-SIMS imaging study of 18th century pastel micro-samples from Maurice Quentin de La Tour. 39èmes Journées Françaises de Spectrométrie de Masse, Sep 2023, Marseille, France. ⟨hal-04157538⟩
- Caroline Bouvier, Philippe Walter, Alain Brunelle, Elisabetta Neri, Nesrine Nasr, et al.. Imaging the stratigraphy on a Roman polychrome colossal statue coated with waxes using Time-of-Flight Secondary Ion Mass Spectrometry. SIMS Europe 2023, Sep 2023, Nottingham (UK), United Kingdom. ⟨hal-04199717⟩
- Gauthier Rosé, Emeline Pouyet, Michel Sablier, Alain Brunelle. Méthode de préparation par enrobage à l’or de papiers de pastels pour l’imagerie ToF-SIMS. Journées Scientifiques Annuelles du GDR-MSI Imagerie par Spectrométrie de Masse, Jun 2023, Villeneuve d'Ascq, France. ⟨hal-04133898⟩
- Gauthier Rosé, Michel Sablier, Alain Brunelle. Multimodal mass spectrometry analysis of organic compounds in old paintings. 39th Informal Meeting on Mass Spectrometry, May 2023, Paris, France. ⟨hal-04133909⟩
- Malmert Aurore, Clarisse Chavanne, Alain Brunelle, Emeline Pouyet. Non-invasive analyses of E. Chevreul’s chromatic circle. Technart 2023 International conference on analytical techniques in art and cultural heritage, May 2023, Lisbonne, Portugal. ⟨hal-04133865⟩
- Alain Brunelle. TOF-SIMS mass spectrometry imaging, from early studies with polyatomic ion beams, applications in natural substances, to old masters paintings. Webinar: University of Gothenburg, Chemical Imaging Infrastucture, MS Imaging Seminar Series, Feb 2023, Göteborg, Sweden. ⟨hal-04029757⟩
- Alain Brunelle. Fine and complex organic-inorganic layers in old paintings revealed by TOF-SIMS mass spectrometry imaging. 10èmes Journées Scientifiques du LabEx CHARMMMAT, Dec 2022, Gif-sur-Yvette, France. ⟨hal-04029699⟩
- Alain Brunelle, Caroline Bouvier, Sven Kayser, Alexander Pirkl, Ewald Niehuis, et al.. A fine analysis of the composition of organic-inorganic complex layers of cross-sections from old paintings by TOF-SIMS imaging, enlightened by MS/MS and Orbitrap. SIMS XXIII 22th International Conference on Secondary Ion Mass Spectrometry, Sep 2022, Minneapolis (MN), United States. ⟨hal-04029818⟩
- Alain Brunelle. From early studies with polyatomic ion beams, to pigments in old master paintings, and natural substances in tropical woods; the exciting journey of time-of-flight secondary ion mass spectrometry. Seminar : Montréal University Mass Spectrometry Discussion Group, Sep 2022, Montréal Québec, Canada. ⟨hal-04029753⟩
- Alain Brunelle. En allant des interactions agrégats-surfaces aux tableaux anciens, en passant par les métabolites de bois tropicaux, avec l’imagerie par spectrométrie de masse d’ions secondaires TOF-SIMS. Séminaire : Institut des Sciences Analytiques, CNRS UMR580, Université de Lyon, Oct 2021, Villeurbanne, France. ⟨hal-04029741⟩
- Alain Brunelle, Lucrèce Matheron. Imageries par Spectrométrie de Masse MALDI et TOF-SIMS au Service du Passé. Séminaire : Muséum National d'Histoire Naturelle, Jun 2021, Paris, France. ⟨hal-04029735⟩
- Caroline Bouvier, Helen Glanville, Laurence de Viguerie, Chiara Merucci, Philippe Walter, et al.. High resolution TOF-SIMS imaging of cross-sections from old paintings. 2021 Rice University SIMS Remote Workshop, Mar 2021, Houston, United States. ⟨hal-04029805⟩
- Elisabetta Neri, Laurence de Viguerie, Caroline Bouvier, Alain Brunelle, Fathi Bejaoui, et al.. The polychromy and wax finishing of an Imperial colossal statue from Thougga in the Bardo collection (Tunisia). Color & Space Interfaces of Ancient Architecture and Sculpture – 10th International Round Table on Ancient Polychromy, Nov 2020, Remote conference, France. ⟨hal-04029793⟩
- Alain Brunelle. Imagerie par spectrométrie de masse TOF-SIMS pour l’analyse de tableaux anciens. Séminaire : Techniques au Top : Formation aux Techniques Emergentes Appliquées au Monde de la Recherche en Histoire et Archéologie et Valorisation des Savoir-Faire, Nov 2020, Paris, France. ⟨hal-04029708⟩
- Alain Brunelle. L’imagerie par spectrométrie de masse d’ions secondaires TOF-SIMS, en 3-D et à moins de 1 micromètre : principes et applications, de l’étude de métabolites de bois tropicaux aux tableaux anciens. Séminaire : Fédération des Sciences Chimiques de Marseille, Aix-Marseille Université, Jan 2020, Marseille, France. ⟨hal-04029728⟩
- Alain Brunelle. TOF-SIMS imaging in 3-D and at less than 1 µm for plant metabolites and cultural heritage. OURCON VII Imaging Mass Spectrometry Conference, Oct 2019, Saint-Malo, France. ⟨hal-04029657⟩
- Alessandra V. Bombace, Caroline Bouvier, Philippe Walter, Antonino Licciardello, Alain Brunelle. TOF-SIMS detection and identification of dyes on textiles from XIX century. SIMS XXII 22th International Conference on Secondary Ion Mass Spectrometry, Oct 2019, Kyoto, Japan. ⟨hal-04029772⟩
- Caroline Bouvier, Helen Glanville, Laurence de Viguerie, Chiara Merucci, Philippe Walter, et al.. Analyses by TOF-SIMS imaging of cross-sections from the Bacchanals paintings of Nicolas Poussin. SIMS XXII 22th International Conference on Secondary Ion Mass Spectrometry, Oct 2019, Kyoto, Japan. ⟨hal-04029764⟩
- Alain Brunelle. From early studies with polyatomic ion beams, to pigments in old master paintings, and natural substances in tropical woods; the exciting journey of time-of-flight secondary ion mass spectrometry. 22th International Conference on Secondary Ion Mass Spectrometry, Oct 2019, Kyoto, Japan. ⟨hal-04029648⟩
- Philippe Walter, Alain Brunelle, Caroline Bouvier, Helen Glanville, Laurence de Viguerie, et al.. Combining in situ analysis of a painting with ToF-SIMS imaging of a sample to understand artistic practices. Advanced Mass Spectrometry In Cultural Heritage Symposium, Jun 2019, Bordeaux, France. ⟨hal-04027552⟩
- Alain Brunelle. TOF-SIMS analysis applied to artworks and museum objects. Summer School Advanced Mass Spectrometry Applied to Cultural Heritage, Jun 2019, Bordeaux, France. ⟨hal-04029690⟩
- Alain Brunelle. Depuis les interactions agrégats-surfaces aux tableaux anciens, en passant par l’imagerie de métabolites de bois tropicaux. Séminaire du groupe de Chimie Structurale Organique et Biologique de l’Institut Parisien de Chimie Moléculaire, May 2019, Paris, France. ⟨hal-04029720⟩
- Alain Brunelle. TOF-SIMS imaging in 3-D and at less than 1 µm for plant metabolites and cultural heritage. International Winter School on Mass Spectrometry, Mar 2019, Palaiseau, France. ⟨hal-04029683⟩
- Alain Brunelle. TOF-SIMS mass spectrometry imaging, from biology and natural substances to old masters paintings. Seminar : University of Nottingham, school of pharmacy, Jan 2019, Nottingham, United Kingdom. ⟨hal-04029749⟩
- L-F Nothias-Scaglia, S. Boutet-Mercey, X. Cachet, H-E de La Torre, J. Costa, et al.. Welcoming the green metabolomic era: supercritical fluid chromatography, tandem mass spectrometry, and molecular networking, as an efficient workflow to explore metabolome and isolate targeted compound. . 9th Joint Natural Products Conference, 2016, Jul 2016, Copenhague, Denmark. ⟨hal-01321704⟩
- Zeina Soayfane, Michela Cantiello, Horst Robenek, Bruno Payré, Alexandre Seyer, et al.. Characterization of cytosolic lipid droplets and their traffic in mouse intestine or Caco-2 cells. FASEB Scientific Research Conference, Federation of American Societies for Experimental Biology (FASEB). USA., Jul 2014, Snowmass, United States. ⟨hal-01580676⟩
- B. Farre, A. Brunelle, O. Laprévote, J.P. Cuif, C.T. Williams, et al.. Couches coquillières de l'huître perlière Pinctada margaritifera : correspondance entre microstructure et composition. 13ème Journée de la Société Française de Biologie des Tissus Minéralisés, May 2011, Paris, France. ⟨hal-00599663⟩
- B. Farre, Y. Dauphin, A. Brunelle. Mollusk shell lipids.. Bivalve biomineralisation archival potential and proxy incorporation., May 2009, Bruxelles, Belgium. pp.42-46. ⟨hal-00509277⟩
- B. Farre, J.P. Cuif, A. Brunelle, O. Laprevote. Biochemical characterizations of the organic matrices of the calcitic prisms of the pearl oyster Pinctada margaritifera. 2nd EuroMinSci Conf, Mar 2008, giens, France. ⟨hal-00407243⟩
- A. Brunelle, S. Bouneau, S. Della Negra, J. Depauw, Y. Le Beyec, et al.. Sputtering and secondary ion emission induced by gold clusters: - Energy and angular distributions. Conference on Desorption 2002, Nov 2002, Estes Park, United States. ⟨in2p3-00014262⟩
- I. Baranov, A. Brunelle, S. Della-Negra, D. Jacquet, S. Kirillov, et al.. Sputtering of nanodispersed targets of gold and desorption of gold nanoclusters (2-100 nm) by 6 MeV Au$_5$ cluster ions. International Conference on Atomic Collisions in Solids 19, Jul 2001, Paris, France. pp.809-815. ⟨in2p3-00011854⟩
- M. Fallavier, R. Kirsch, J.-C. Poizat, J. Remillieux, J.-P. Thomas, et al.. Collisions d'agregats d'or dans les solides : emissions de surface et degats d'irradiation. Journees Nationales de Radiochimie Chimie Nucleaire 7, Sep 2000, St Remy Les Chevreuse, France. ⟨in2p3-00010702⟩
- M. Most, K. Wien, A. Brunelle, S. Della Negra, J. Depauw, et al.. H$^+_2$,H$^+_3$ and H$^+_4$ emission by MeV ion impact: charge state dependence of energy and angular distributions. International Conference on Atomic Collisions in Solids 18, Aug 1999, Odense, Denmark. pp.772-784. ⟨in2p3-00010854⟩
- Y. Le Beyec, K. Baudin, A. Brunelle, S. Della-Negra, D. Jacquet, et al.. Desorption and sputtering from solids induced by polyatomic projectiles. Desorption'98, Sep 1998, Rio De Janeiro, Brazil. pp.428-431. ⟨in2p3-00014771⟩
- A. Brunelle, S. Della-Negra, J. Depauw, D. Jacquet, Y. Le Beyec, et al.. Collisions of fast clusters with solids and related phenomena. International Conference on Large-Scale Collective Motion of Atomic Nuclei, Oct 1996, Messina, Italy. pp.293-306. ⟨in2p3-00008029⟩
- K. Wohrer, M. Chabot, J. P Rozet, D. Gardès, Dominique Vernhet, et al.. Capture and ionization cross sections in 10 MeV C5+ cluster-helium collisions. THE 8th INTERNATIONAL CONFERENCE ON THE PHYSICS OF HIGHLY CHARGED IONS (HCI-1996), Sep 1996, Omiya, Saitama, Japan. pp.284-285, ⟨10.1088/0031-8949/1997/T73/093⟩. ⟨hal-00008793⟩
- M. Chabot, K. Wohrer, J. P Rozet, D. Gardès, Dominique Vernhet, et al.. Fragmentation patterns of ionized C5Q+ clusters (Q = 1 → 4). THE 8th INTERNATIONAL CONFERENCE ON THE PHYSICS OF HIGHLY CHARGED IONS (HCI-1996), Sep 1996, Omiya, Saitama, Japan. pp.282-283, ⟨10.1088/0031-8949/1997/T73/092⟩. ⟨hal-00014027⟩
- K. Boussofiane-Baudin, G. Bolbach, A. Brunelle, S. Della-Negra, P. Hakansson, et al.. Secondary ion emission under cluster impact at low energies (5-60 KeV), influence of the number of atoms in the projectile. Conference on Polyatomic Ion Impact on Solids and Related Phenomena, Jun 1993, Saint-Malo, France. pp.160-163. ⟨in2p3-00015984⟩
- K. Boussofiane-Baudin, A. Brunelle, P. Chaurand, S. Della-Negra, J. Depauw, et al.. Non-linear sputtering effects induced by mev energy gold clusters. Conference On Polyatomic Ion Impact On Solids And Related Phenomena, Jun 1993, Saint-Malo, France. pp.61-68. ⟨in2p3-00015983⟩
- S. Della Negra, Y. Le Beyec, A. Brunelle, B. Waast, D. Gardes, et al.. Orion projet: acceleration of clusters ions and highly charged biomolecules from 10 mev to 1 gev. European Research Conference On Prospect For Heavy Ion Fusion, Sep 1992, Aghia Pelaghia, Greece. ⟨in2p3-00011170⟩
- M. Benguerba, A. Brunelle, S. Della-Negra, J. Depauw, H. Joret, et al.. A new concept: the fast preequilibrium charge state of swift ions in solids. A NATO Advanced Research Workshop on Methods and Mechanisms for Producing Ions from Large Molecules, Jun 1990, Minaki Lodge, Canada. pp.19-25. ⟨in2p3-00016151⟩
- A. Brunelle, M. Benguerba, S. Della-Negra, J. Depauw, H. Joret, et al.. Cluster ion projectiles as a probe for desorption-ionization of large molecules and surface analysis. comparison with fission fragments from $^{252}$Cf. Asms Conference on Mass Spectrometry and Allied Topics 38, Jun 1990, Tucson, United States. pp.447-448. ⟨in2p3-00016077⟩
- A. Brunelle, S. Della-Negra, J. Depauw, H. Joret, Y. Le Beyec, et al.. Equilibrium charge state of fast heavy ions in solids measurements of post-ionization effects. Highly Charge Ions: New Physics and Advanced Techniques, Mar 1989, Berkeley, United States. pp.484-489. ⟨in2p3-00016375⟩
Poster de conférence4 document
- C. Cerruti, Laëtitia Théron, David Touboul, Thierry Astruc, Alain Brunelle. Analyse lipidomique de foie gras de canard de différents classements commerciaux à l’aide de l’imagerie par spectrométrie de masse TOF-SIMS. Congrès de Spectrométrie de Masse et d’Analyse Protéomique (SMAP), Sep 2011, Avignon, France. ⟨hal-04721550⟩
- N. Wehbe, M. Fallavier, S. Della Negra, J. Depauw, A. Brunelle, et al.. Sputtering and secondary ion emission under gold cluster impact: Cluster size and velocity dependences of the yields. Desorption 2010, May 2010, Seillac, France. ⟨in2p3-00589526⟩
- Anne Héron, Vanessa W Petit, Alexandre Seyer, Farida Benabdellah, David Touboul, et al.. BRAIN GLYCEROPHOSPHOLIPIDS AND CHOLESTEROL IMAGING BY MASS SPECTROMETRY. 1ère Journée de l’Institut Médicament-Toxicologie-Chimie-Environnement, Apr 2010, Paris, France. ⟨hal-01609936⟩
- Thorsten Schramm, Alfons Hester, Ivo Klinkert, Ron M. A. Heeren, Markus Stoeckli, et al.. COMPUTIS ML - a standardised data format for imaging mass spectrometry. 18th International Mass Spectrometry Conference, Aug 2009, Bremen, Germany. ⟨cea-03086153⟩
Chapitres d'ouvrage5 document
- C. Bouvier, A. Brunelle, Sebastiaan van Nuffel. Transferable Mass Spectrometry Methods: Examination of Authenticity in Artwork. Applications of Mass Spectrometry for the Provision of Forensic Intelligence, Royal Society of Chemistry, pp.236-264, 2023, ⟨10.1039/BK9781837671922-00236⟩. ⟨hal-04357798⟩
- Sebastiaan van Nuffel, Alain Brunelle. TOF-SIMS Imaging of Biological Tissue Sections and Structural Determination Using Tandem MS. Young-Jin Lee. Mass Spectrometry Imaging of Small Molecules: Methods and Protocols, 2437, Springer US, pp.77-86, 2021, Methods in Molecular Biology, 978-1-0716-2029-8. ⟨10.1007/978-1-0716-2030-4_5⟩. ⟨hal-03479024⟩
- David Touboul, Alain Brunelle. MALDI mass spectrometry imaging of lipids and primary metabolites on rat brain sections. Mass Spectrometry Imaging of Small Molecules, series: Methods in Molecular Biology, Humana Press, 1203, Springer New York, pp.41-48, 2015, 978-1-4939-1356-5. ⟨10.1007/978-1-4939-1357-2_5⟩. ⟨hal-01170403⟩
- David Touboul, Alain Brunelle. TOF-SIMS imaging of lipids on rat brain sections. Lin He. Mass Spectrometry Imaging of Small Molecules, 1203, Springer New York, pp.21-27, 2015, Methods in Molecular Biology, 978-1-4939-1356-5. ⟨10.1007/978-1-4939-1357-2_3⟩. ⟨hal-01170395⟩
- David Touboul, Olivier Laprévote, Alain Brunelle. Medical and biological applications of cluster-ToF-SIMS. Vickerman, J.C. Briggs, D., Eds. ToF-SIMS: Surface analysis by mass spectrometry, 2nd edition, IM Publications and Surface Spectra Limited, pp.583-612, 2013, ⟨10.1255/tof2ch22⟩. ⟨hal-00908712⟩
Autres publications1 document
- Anne Héron, Alain Brunelle, Charles Duyckaerts, Létitia Gamiette, Adina N Lazar, et al.. Lipidomique - Neuroinflammation - Alzheimer : Lipidomique Localisée de Cerveaux de Patients atteints de la Maladie d'Alzheimer en Imagerie par Spectrométrie de Masse. 2009. ⟨hal-01613986⟩
Pré-publications, Documents de travail1 document
- Landry Blanc, Alain Brunelle, Cecile Courreges, Nicolas Desbenoit, Isabelle Fournier, et al.. Imagerie par spectrométrie de masse : principes et applications. 2021. ⟨hal-03954524⟩
Thèses1 document
- A. Brunelle. Spectrometrie de masse par temps de vol a multisonde de desorption-ionisation (photons U.V. et particules KeV et MeV). Des atomes aux agregats comme projectiles.. Instrumentation and Detectors [physics.ins-det]. Université Paris Sud - Paris XI, 1990. English. ⟨NNT : ⟩. ⟨in2p3-00014975⟩